Abstrack: Abstract: SAVI approach is student learning process with combining physical motion, intellectual activity and using all sensory so it can well influence of learning. SAVI approach combines four component influencing for learning in the class. The fourth learning method must have in order to learn continue optimally SAVI is an acronym for somatic (s) meaning motion, auditory (A) meaning that learning by listening, visual (v) meaning that learning uses eyes sensory, intellectual(I) meaning that learning uses mind skill. This research has purpose to know process and result by developing of biological substance based on SAVI approach developing of this learning material uses Borg and Gall method the result of this research is learning material as student book. The result of research shows that validation result by expert validator is valid with the average 87,98 percent and test of small group is gotten that reading skill of student book shows valid criteria by all complement. It means that the students can understand the book easily. The result shows that the average of each complement from 79,78 to 100 so it is very valid. The student book use based on SAVI approach can improve study output and student motivation it can be seen from the average score between pretest and post test then starting motivation of the student before using the student book and ending motivation of the student after using the student book that there is increase.